diff --git a/.git-blame-ignore-revs b/.git-blame-ignore-revs
index 725cb56e7..003345913 100644
--- a/.git-blame-ignore-revs
+++ b/.git-blame-ignore-revs
@@ -10,3 +10,5 @@ a265c6267e75c831b8294a760f94b9d6cffb92ea
 09c2a08d113b2194697fc0a3925d569184babe97
 # misc: apply djhtml (#69422)
 8251b8188fb57414214ace63459156b43ddda46d
+# misc: apply django-upgrade (#69426)
+0bec12d61de2de7f812f5055de2724942beeedb5
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 1c607f2f6..030c42fbd 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -6,6 +6,11 @@ repos:
     hooks:
     - id: pyupgrade
       args: ['--keep-percent-format', '--py37-plus']
+-   repo: https://github.com/adamchainz/django-upgrade
+    rev: 1.10.0
+    hooks:
+    - id: django-upgrade
+      args: ['--target-version', '2.2']
 -   repo: https://github.com/psf/black
     rev: 22.3.0
     hooks:
diff --git a/README b/README
index 987a51e89..469b03aa3 100644
--- a/README
+++ b/README
@@ -91,9 +91,12 @@ djhtml is used to automatically indent html files, using those parameters:
 
     djhtml --tabwidth 2
 
-There is .pre-commit-config.yaml to use pre-commit to automatically run black,
-isort, pyupgrade, and djhtml before commits. (execute `pre-commit install`
-to install the git hook.)
+django-upgrade is used to automatically upgrade Django syntax, using those parameters:
+
+    django-upgrade --target-version 2.2
+
+There is .pre-commit-config.yaml to use pre-commit to automatically run these tools
+before commits. (execute `pre-commit install` to install the git hook.)
 
 Support
 =======